<blockquote><b>Quoting A.D.A's Momma(;:</b>" my brother passed away and he was like my dad... his name was Andrew. but i called him Drew . i figured Drew Barrymore ? and thought it could be used as a middle name... "</blockquote>
I would use a femal variation of his name as opposed to drew, like Andrea. Or use drew as her middle name but with a more feminine first name to balance. Info thin it works as a middle name for a girl in some instances but not with a clearly male first name like Tristan. Audrey is a girl's name but it doesn't flow with drew at all.
I love Audrey Hepburn, but a person i used to know went by the name Audrey and completely ruined the name for me.