Quoting susanesque:" If possible I would leave at a time when he'd sleep for a while. Take lots of breaks. I think it's be worth it!"
Quoting Hannah.:" Well depends how your LO does in the car. My son would be miserable, or sleep through a lot of it and ... [snip!] ... his sleeping schedule. (And its hard to get him back to normal, he fights sleep like crazy!) So I don't think I would. "
Quoting Chim Richalds:" Could you possibly take a bus? I would probably do it, but I would try to do it when he will be sleeping at least for a good chunk of time."